Polydeoxyribonucleotide PDRN

Polydeoxyribonucleotide (PDRN) is a biologically active compound derived from purified fragments of DNA, typically obtained from salmon sperm. It is a polymer of deoxyribonucleotides with an average molecular weight between 50–1500 kDa.

Key Points about Polydeoxyribonucleotide (PDRN):

1. Structure & Nature

• Composed of DNA fragments (chains of deoxyribonucleotides).
• Naturally occurring, highly biocompatible, and safe for medical applications.

2. Medical & Therapeutic Uses

• Tissue regeneration: Stimulates cell growth, angiogenesis (new blood vessel formation), and wound healing.
• Anti-inflammatory effect: Modulates cytokine release and reduces inflammation.
• Skin rejuvenation & aesthetics: Used in dermatology and cosmetic medicine to improve skin elasticity, hydration, and anti-aging effects.
• Orthopedics: Assists in tendon and ligament healing, and reduces pain in musculoskeletal injuries.
• Diabetic ulcers & chronic wounds: Enhances healing and tissue repair.
• Anti-hair loss：
• Reproductive Health and Male Infertility: Protamine is rich in arginine, which stimulates the pituitary gland to release gonadotropins, enhances liver function, and treats male infertility caused by insufficient semen secretion and sperm deficiency. Furthermore, the trace element zinc in fish sperm DNA can increase plasma testosterone levels and sperm count, synergizing with arginine and DNA to improve semen quality.