【CAS No.】 9009-65-8
【Formula 】NA

【National Medicine Permission Number】 H11020228

【Drug Class】 anti-heparin drugs

【Formulation Use】Protamine sulfate injection（1）5ml：50mg （2）10ml：100mg

【Packing Specification】1kg/barrel、5kg/Barrel

【Standard】 CP, EP,USP,BP ,ect 

【Description】:

Protamine sulfate is indicated for counteracting or reversing the anticoagulant effect of heparinas necessary. Such reversal may, for example, be required often before surgery; after renalhemodialysis; post open heart surgery; whenever excessive bleeding results from heparin use;and/or for the treatment of heparin overdosage, among other similar or related circumstances.

Protamine sulfate may be administered undiluted (10mg/mL). Alternatively, dilute protamine sulfate (10mg/mL) with equal parts sodium chloride 0.9%. This results in a solution of 5mg/mL protamine sulfate.
Infuse over at least 10 minutes. Maximum infusion rate 5mg/minute. Too rapid administration can cause hypotension, dyspnoea and bradycardia, as well as increase the risk of severe hypersensitivity reactions